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Combined electrical and optical recording of multi-scale neural circuit dynamics

In this webinar, Chris Lewis from Fritjof Helmchen's lab showcases new approaches for electrophysiological recordings using our silicon neural probes and surface arrays combined with diverse optical methods such as wide-field or 2-photon imaging, fiber photometry, and optogenetic perturbations in awake, behaving mice.
 
Multi-modal recording of single units and local field potentials across cortex, hippocampus and thalamus alongside calcium activity via GCaMP6F in cortical neurons in triple-transgenic animals or in hippocampal astrocytes via viral transduction are brought to bear to reveal hitherto inaccessible and under-appreciated aspects of coordinated dynamics in the brain.
 

Chris is a neuroscientist and engineer currently doing a post-doc in Fritjof Helmchen's Laboratory of Neural Circuit Dynamics where he combines his multidisciplinary skills in the pursuit of the development of next-generation brain-computer-interfaces.