---
title: Deep-brain optogenetics without intracranial surgery
description: Learn from Felicity Gore about using the novel ChRmine opsin for non-invasive optogenetic stimulation of deep brain targets such as the VTA and BLA
---

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# [Deep-brain optogenetics without intracranial surgery](https://neurons.cambridgeneurotech.com/webinars/s2e2)

 Written by [Cambridge NeuroTech](https://neurons.cambridgeneurotech.com/webinars/author/cambridge-neurotech) | May 26, 2021

Felicity Gore from Karl Deisseroth's lab describes ChRmine; a novel, red-shifted opsin with high-sensitivity and strong activation dynamics that can drive robust neural responses in deep targets from light delivered from OUTSIDE the skull, thereby removing the need to place often bulky fiber optic cannulas in the brain tissue.

Reference:

[https://www.nature.com/articles/s41587-020-0679-9](https://www.nature.com/articles/s41587-020-0679-9)

 

[View full post](https://neurons.cambridgeneurotech.com/webinars/s2e2)

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